Propranolol is a beta-adrenergic blocking agent that is used for treating high blood pressure, heart pain (angina), abnormal rhythms of the heart, and some neurologic conditions. Examples of other beta-adrenergic blockers include metoprolol (Lopressor), atenolol (Tenormin), and timolol (Blocadren). This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- The net physiologic effect of beta-adrenergic blockade is usually advantageous and is manifested during exercise by delayed onset of pain and increased work capacity.
- However, research suggests that more studies are needed to determine the effectiveness and safety of taking propranolol for this use.
- It decreases blood pressure by relaxing blood vessels and slowing heart rate.
- Any chloride deficit is generally mild, and usually does not require specific treatment except under extraordinary circumstances (as in liver or renal disease).
- If you take these drugs together, your doctor should monitor your blood pressure.
For migraines, treatment can last for several months or years, depending on how bad your symptoms are. For more information about how propranolol can affect you and your baby during pregnancy, visit the Best Use of Medicines in Pregnancy (BUMPS) website. It’s important to treat your high blood pressure to keep you well. These common side effects happen in more than 1 in 100 people.
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Inderal (propranolol hydrochloride) is a beta-adrenergic receptor blocking agent used for control of hypertension. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. No information is available on the relationship of age to the effects of propranolol oral solution in geriatric patients.
Blunting of the antihypertensive effect of beta-adrenoceptor blocking agents by nonsteroidal anti-inflammatory drugs has been reported. Optimum reduction of essential tremor is usually achieved with a dose of 120 mg per day. Occasionally, it may be necessary to administer 240 mg to 320 mg per day.
It treats conditions like high blood pressure, tremors and atrial fibrillation. It can also prevent migraine headaches by relaxing the blood vessels in your brain. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
Propranolol, oral tablet Images
Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include fezolinetant, propafenone, thioridazine, among others.
If progressive renal impairment becomes evident, consider withholding or discontinuing diuretic therapy. Hypokalemia may develop, especially with brisk diuresis or when severe cirrhosis is present. Thyroxine may result in a lower than expected TS concentration when used concomitantly with propranolol. Antipyrine and lidocaine have reduced clearance when used concomitantly with propranolol.
When taken with warfarin (Jantoven), propranolol can increase the amount of warfarin in your body. This may cause an increase in how long you bleed from any wound. Your warfarin dosage may need to be changed if you take these drugs together. If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist. After you take a single dose of propranolol, half of the drug will be eliminated from your body in about 6 hours.
Does propranolol cause weight gain?
Central nervous system (CNS) side effects of propranolol include short-term memory loss. Follow all directions on your prescription label and read all medication guides or instruction sheets. Co-administration of chlorpromazine with propranolol resulted in a 70% increase in propranolol plasma level.
Hemangeol® may increase the risk of heart or blood vessel problems (eg, bradycardia, hypotension). In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs.
Propranolol has been studied for anxiety, but right now there is not enough evidence to support its use. More clinical studies are needed to determine whether propranolol is a safe and effective drug for treating any anxiety disorder. Yes, it’s possible that propranolol may affect your memory.
Thiazides should also be used with caution in patients with impaired hepatic function or progressive liver disease, since minor alterations of fluid and electrolyte balance may precipitate hepatic coma. Thiazides may decrease serum FBI levels without signs of thyroid hallucinogens effects, addiction potential and treatment options disturbance. Thiazide drugs may increase the responsiveness to tubocurarine. Theophylline clearance is reduced when used concomitantly with propranolol. Hypotension and cardiac arrest have been reported with the concomitant use of propranolol and haloperidol.
Weight gain may occur in some patients using propranolol, a beta-blocker, but it does not appear to be a common side effect. The manufacturer does not list weight gain as a side effect, but several reviews, anecdotal reports and case studies have reported weight gain. A study of the beta-blocker class found that about 1.2 kg (2.6 lbs) of weight was gained in patients overall, possibly due to lowered energy metabolism. Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Propranolol will add to the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system and may cause drowsiness.
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The pharmacokinetics of oxazepam, triazolam, lorazepam, and alprazolam are not affected by co-administration of propranolol. Co-administration of theophylline with propranolol decreases theophylline oral clearance by 30% to 52%. The mean Cmax and AUC of propranolol are pregabalin abuse in combination with other drugs increased, respectively, by 50% and 30% by co-administration of nisoldipine and by 80% and 47%, by co-administration of nicardipine. The metabolism of lidocaine is inhibited by co-administration of propranolol, resulting in a 25% increase in lidocaine concentrations.
If you suddenly stop taking propranolol, you may experience serious heart problems such as angina (chest pain), heart attack, or an irregular heartbeat. Your doctor will probably want to decrease your dose gradually over 1 to 2 weeks. Your doctor will watch you carefully and will probably tell you to avoid physical activity during this time. Propranolol belongs to a group of medicines called beta blockers.
